Assemble is a free and open source, easy to use software that proposes an intuitive graphical interface to study and construct complex three-dimensional RNA structures.
When an RNA tertiary structure is opened with Assemble, it is automatically annotated with a secondary structure definition.
This secondary structure can be used as a map to analyze the original tertiary structure.
Using a secondary structure definition, Assemble can also produce a first draft of a 3D Model. Then the construction process can be pursued "by hand" using several widgets.
Here are some key features of "Assemble":
· prediction of RNA secondary structures
· interactive RNA secondary structure construction and visualization
· semi-automatic generation of RNA 3D models
· connection between the 2D and 3D panels
· torsion angles alteration for any single residue
· translation and rotation of any element from a few atoms to a whole molecule
· easy cut, link of any molecular chains
· ability to manage your own RNA structural library using the MyPDB panel
· ability to search for and save RNA structural motifs to easily fold a 3D region
· embedded refinement tool
· mono and stereo views
· all the computer-intensive tasks are delegated to RNA WebServices
· entirely developed with the Java language. Runs on Windows, Linux and MacOSX
· OpenGL-powered application thanks to the JOGL API project
· open source (MIT) license and free
Requirements:
· Java 1.5 or later
What`s New in This Release: [ read full changelog ]
· It fixes the automatic update system for Windows.